Adult onset retinoblastoma
نویسندگان
چکیده
Retinoblastoma (RB) is the most common primary malignant intraocular tumor of childhood presenting usually before 5 years of age. RB in adults older than 20 years is extremely rare. A literature search using PubMed/PubMed Central, Scopus, Google Scholar, EMBASE, and Cochrane databases revealed only 45 cases till date. Over the past decade, there has been a significant increase in the number of such reports, indicating heightened level of suspicion among ophthalmologists. Compared to its pediatric counterpart, adult onset RB poses unique challenges in diagnosis and treatment. This article summarizes available literature on adult onset RB and its clinical and pathologic profile, genetics, association with retinocytoma, diagnostics, treatment, and outcomes.
منابع مشابه
Unusually very late-onset new growth of intraocular retinoblastoma: A case report and review of literature
Purpose To report a patient who presented with a very late-onset new growth of intraocular retinoblastoma, which occurred 11 years after the initial combined treatment. Observations A 12-year-old monoophthalmic female patient presented with bilateral familial retinoblastoma showing new growth of intraocular tumor after 11 years of complete regression following combined local and systemic trea...
متن کاملCharacterization of some glycolytic enzymes from human retina and retinoblastoma.
GLycolytic enzymes were studied from normal human retinas (both fetal and adult) and from retinoblastomas of eight patients and an established retinoblastoma cell line. No significant differences were found between the enzyme activities in the tissues investigated except for hexokinase and pyruvate kinase, which were significantly decreased in the tumor cells. In fetal retina, five different fo...
متن کاملEpidemiological pattern of retinoblastoma at the Philippine General Hospital
Results The incidence of retinoblastoma increased from 40/100,000 new cases in 1967 to 1977 to 237/100,000 new cases in 1997 to 2001. The average age at onset did not change over time but the age at consultation decreased from 1.5 years to 1 year. The most common initial ocular manifestation at onset was cat’s eye reflex (77 to 79%) with findings of leukocoria (67 to 77%). Extraocular findings ...
متن کاملRetinoblastoma in Adults: a Case Report and Literature Review
PURPOSE To report a case of adult retinoblastoma with a wrong diagnosis of melanoma. CASE REPORT Herein, we present an adult retinoblastoma case who was misdiagnosed as melanoma in fine-needle aspiration biopsy with intravitreal hemorrhage and later neovascular glaucoma after biopsy. The diagnosis of retinoblastoma was confirmed after enucleation. CONCLUSION Retinoblastoma should be conside...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 64 شماره
صفحات -
تاریخ انتشار 2016